Ten of the newest Purdue technologies available to license

The Purdue Research Foundation Office of Technology Commercialization updates the innovations on its Available Technologies page on a regular basis. Over the course of a month, the hundreds of innovations already on the page are joined by dozens of others; all are available for licensing and other commercialization activities. 

These are 10 of the newest technologies listed on the OTC website: 

Discovery of Potent Protease Inhibitors for Covid-19 Treatment. 2020-GHOS-69088 

  • Researchers at Purdue University have developed potent inhibitors for the SARS-CoV-2 protease enzyme 3CLpro. Covid-19, an infection caused by the SARS-CoV-2 virus, has led to an ongoing global pandemic. Currently, no effective drug treatment is available for Covid-19. To find a potential therapeutic for Covid-19, Purdue researchers discovered a series of novel noncovalent functionalized bis-amide derivatives that were previously reported to inhibit a SARS-CoV-2 enzyme, 3CLpro. 

A Low-Speed, High-Torque Hydrostatic Powertrain for Renewable Energy Application. 2021-SHAN-69450 

  • Researchers at Purdue University have developed a transmission system that uses an adaptive transmission ratio, allowing for the optimization of the speed and torque going into the generator. This approach improves system efficiency, while also allowing for individual control of turbines and generators across an array, leading to the potential for networks of systems that work cohesively for maximum efficiency. This technology is also capable of using water as a working fluid, which minimizes the environmental impact of leakages. 

Microneedle Patch for Wound Oxygenation and Biofilm Eradication. 2021-RAHI-69535 

  • Purdue University researchers have developed a flexible microneedle array on a polyethylene terephthalate (PET) support that can puncture biofilms and provide oxygen and antibiotics to the wound site. The microneedle array is effective for decontamination and increasing the healing process of wounds. Specifically, it increased the wound’s oxygen content by 50 percent, killed all gram-positive bacteria within 24 hours, and killed all gram-negative bacteria within 12 hours. 

Mussel-Inspired Adhesives Containing Gallol Groups. 2022-WILK-69827 

  • Researchers at Purdue University have developed a new class of adhesive polymers with gallol groups. Gallol groups are similar to catechol groups found in mussel adhesive proteins that give mussels the characteristic ability to adhere on universal substrates. Many of the current adhesives have performance limitations including the ability to adhere well to wet surfaces or underwater conditions. The Purdue researchers proposed two synthesis mechanisms to produce different classes of gallol-containing copolymers. These adhesives showed superior bonding characteristics in both dry and wet conditions. 

Novel Building Envelope Materials with Enhanced Durability that Reduce Energy Consumption. 2022-VELA-69766 

  • Researchers at Purdue University have developed a new process to incorporate phase change materials (PCMs) into construction materials. The Purdue researchers’ method involves incorporating the PCMs into construction materials after they’ve already formed, thereby increasing strength and enhancing durability while increasing the thermal inertia of the material. This method can be used to turn bricks, concrete panels and drywall into materials that store thermal energy, reducing energy consumption of heating and cooling, improving thermal comfort and making buildings more energy resilient against power outages and energy crises. 

Pressure-Sensing Prosthetic Socket. 2022-NORT-69699 

  • Students at Purdue University have proposed technology using sensors to detect pressure in transtibial prosthetic sockets. Every year 34,5000 individuals undergo a transtibial amputation, which is the most common type of amputation. Despite the number of people with transtibial prosthetics, transtibial prosthetic sockets are uncomfortable and can cause skin irritation and infection of the residual limb. The Purdue technology helps prevent skin damage and infection by alerting the patient with a notification to their smartphone if a pressure value above the patient-specific level is detected. 

Silicone Padding Embedded in Fabric. 2019-NAUM-68593 

  • Researchers at Purdue University have developed a new silicone padding which can be embedded into woven and nonwoven fabrics such as protective equipment and sporting equipment. Various compositions of this padding have been tested under applied force to create a material with strong response to impact. In addition, sensors can be added to the silicone padding to notify users if the material is being worn down and may need to be replaced, which helps to ensure user safety. 

StoryMakAR: Augmented Reality that Brings Stories to Life. 2020-RAMA-68962 

  • Researchers at Purdue University have integrated a new toolkit to teach augmented reality (AR) and computer programming to K-12 students while encouraging skills in technology, communication, collaboration and creativity through storytelling. It combines block programming, plug-and-play controls and low-fidelity prototyping materials. This setup is compatible with a smartphone application, which allows students to have easier accessibility to software programs. 

Surface Cleaning Validation Using Mass Spectrometric Analysis. 2015-CHOO-67146 

  • To simplify the surface cleaning validation technique, researchers at Purdue University have developed a method for ambient surface cleaning and sampling using real-time mass spectrometric analysis. It is both a continuous and noncontinuous analysis. Sample preparation or sample pretreatment is not required; the entire process can be done within one to two minutes. Hence, this technology is a cost-effective and efficient method of surface cleaning validation that can be incorporated in industry. 

System and Method for Sample Analysis Using Swabs. 2018-COOK-68114 

  • Researchers at Purdue University have developed a new approach to test biological samples with noninvasive, nondestructive swabs. The approach developed by the Purdue researchers is a new technique (swab spray MS) that includes an ambient ionization method in which a minute amount of sample (e.g. tissue) is transferred to a swab tip by a gentle touch, and subsequently ionized with the application of solvent to the swab tip and of high voltage to the swab shaft. 

The Purdue Research Foundation Office of Technology Commercialization is looking for commercialization partners for almost 2,100 technologies that span 19 domains. To find the technology that fits your needs, email otcip@prf.org.